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The detection of Helicobacter pylori cag pathogenicity islands (PAIs) and expression of matrix metalloproteinase-7 (MMP-7) in gastric epithelial dysplasia and intramucosal cancer.

Authors
  • Chung, Woo Chul
  • Jung, Sung Hoon
  • Lee, Kang-Moon
  • Paik, Chang Nyol
  • Kawk, Jea Wuk
  • Jung, Ji Han
  • Lee, Min Kyoung
  • Lee, Yun Kyung
Type
Published Article
Journal
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association
Publication Date
Aug 01, 2010
Volume
13
Issue
3
Pages
162–169
Identifiers
DOI: 10.1007/s10120-010-0552-5
PMID: 20820985
Source
Medline
License
Unknown

Abstract

Our results suggest that infection with a virulent H. pylori strain was associated with early-stage gastric cancer and that carcinogenesis was associated with cag PAI-dependent MMP-7 upregulation.

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