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Detection of helicobacter pylori in bronchoalveolar lavage of patients with chronic obstructive pulmonary disease by real time polymerase chain reaction.

Authors
  • Samareh Fekri, Mitra
  • Hashemi Bajgani, Seyed Mehdi
  • Rasti, Atefe
  • Yazdani, Rostam
  • Mollaie, Hamid Reza
Type
Published Article
Journal
Jundishapur journal of microbiology
Publication Date
Jan 01, 2015
Volume
8
Issue
1
Identifiers
DOI: 10.5812/jjm.14551
PMID: 25789128
Source
Medline
Keywords
License
Unknown

Abstract

These findings can justify the hypothesis of direct injury and chronic inflammation via inhalation and aspiration resulting in H. pylori colonization. In fact, it is thought that H. Pylori infection, beside the host genetic vulnerability and other environmental risk factors might make the patient susceptible to COPD or lead to COPD worsening. Although we found H. pylori infection in some patients with COPD, the results of this study, could not explain the pathogenic mechanisms of COPD.

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