Affordable Access

Access to the full text

Detection of brain metastases using alternative magnetic resonance imaging sequences: a comparison between SPACE and VIBE sequences

Authors
  • Kongpromsuk, Sutasinee1
  • Pitakvej, Nantaporn2
  • Jittapiromsak, Nutchawan2
  • Prakkamakul, Supada2
  • 1 Burapha University, Thailand , (Thailand)
  • 2 Chulalongkorn University, Thailand , (Thailand)
Type
Published Article
Journal
Asian Biomedicine
Publisher
Sciendo
Publication Date
Jul 13, 2020
Volume
14
Issue
1
Pages
27–35
Identifiers
DOI: 10.1515/abm-2020-0005
Source
De Gruyter
Keywords
License
Green

Abstract

BackgroundAccurate identification of brain metastases is crucial for cancer treatment.ObjectivesTo compare the ability to detect brain metastases of two alternative types of contrast-enhanced three-dimensional (3D) T1-weighted sequences called SPACE (Sampling Perfection with Application optimized Contrasts using different flip angle Evolutions) and VIBE (Volumetric Interpolated Brain Sequence) on magnetic resonance imaging (MRI) at 3 tesla.MethodsBetween April 2017 and February 2018, 27 consecutive adult Thai patients with a total number of 424 brain metastases were retrospectively included. The patients underwent both contrast-enhanced 3D T1-weighted SPACE and 3D T1-weighted VIBE MRI sequences at 3 tesla. Two neuroradiology experts independently reviewed the images to determine the number of enhancing lesions on each sequence. Wilcoxon signed rank test was used to compare the difference between the numbers of detectable parenchymal enhancing lesions. Interobserver reliability was calculated using intraclass correlation.Results3D T1-weighted SPACE detected more parenchymal enhancing lesions than 3D T1-weighted VIBE (424 vs. 378 lesions, median 6 vs. 5, P = 0.008). Fifteen patients (55.6%) had equal number of parenchymal enhancing lesions between two sequences. 3D T1-weighted SPACE detected more parenchymal enhancing lesions (up to 9 more lesions) in 10 patients (37%), while 3D T1-weighted VIBE detected more enhancing lesions (up to 2 more lesions) in 2 patients (7.4%). Interobserver reliability between the readers was excellent.ConclusionContrast-enhanced 3D T1-weighted SPACE sequence demonstrates a higher ability to detect brain metastases than contrast-enhanced 3D T1-weighted VIBE sequence at 3 tesla.

Report this publication

Statistics

Seen <100 times