The results of blood testing for HIV antibodies in 4567 volunteer blood donors are reported. Serum samples were collected from high risk groups in Bihar, India. These groups included patients from skin/venereal disease clinics, blood donors, local police, and hospital patients and attendants. Both SERODIA-HIV kits and Wellcozyme anti-HTLV III/Wellcozyme HIV recombinant kits were used to detect HIV infections. All sera were also analyzed using the VDRL flocculation test. None of the sera tested positive for HIV antibodies. 6.94% (206/2966) of the blood donor group tested positive using VDRL, while 4.96% (69/1392) of the skin/venereal disease patients tested positive with VDRL.