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Detection of Alzheimer pathology in vivo using both 11C-PIB and 18F-FDDNP PET.

Authors
  • Tolboom, Nelleke
  • Yaqub, Maqsood
  • van der Flier, Wiesje M
  • Boellaard, Ronald
  • Luurtsema, Gert
  • Windhorst, Albert D
  • Barkhof, Frederik
  • Scheltens, Philip
  • Lammertsma, Adriaan A
  • van Berckel, Bart N M
Type
Published Article
Journal
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Publication Date
Feb 01, 2009
Volume
50
Issue
2
Pages
191–197
Identifiers
DOI: 10.2967/jnumed.108.056499
PMID: 19164243
Source
Medline
License
Unknown

Abstract

Differences in BPND between patients with AD, patients with MCI, and controls were more pronounced for 11C-PIB. The difference in regional binding, the moderate correlation, and the discrepant findings in MCI suggest that they measure related, but different, characteristics of the disease.

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