A description of two cases of factor V deficiency.
- Authors
- Type
- Published Article
- Journal
- Haemophilia : the official journal of the World Federation of Hemophilia
- Publication Date
- Jul 01, 1995
- Volume
- 1
- Issue
- 3
- Pages
- 200–201
- Identifiers
- DOI: 10.1111/j.1365-2516.1995.tb00069.x
- PMID: 27214541
- Source
- Medline
- Keywords
- Language
- English
- License
- Unknown
Abstract
We report two cases of factor V deficiency. A 12-year-old girl with thalassemia major was admitted for bone marrow transplant (mismatched). She was found to have a heterozygous deficiency of factor V (21%), but this was considered compatible with the transplant, which was performed without the support of suppernatant cryoprecipitate. A 14-year-old girl (factor V 2%) with a negative history (menarche at age 12, menstrual cycle regular and normal in quantity and length). One year previously she had complained of menorrhagia (length of period, 9 days); tests revealed server anaemia (Hb 4.9 g/dl). We show how even severe cases of factor V deficiency may often be silent, and not require transfusion in surgical procedures, thus avoiding the risks associated with such therapy.
