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Depression in the early stages of Pick's disease.

Authors
  • Suzuki, H
  • Kuroda, S
  • Ishizu, H
  • Fujisawa, Y
  • Sasaki, K
Type
Published Article
Journal
Acta medica Okayama
Publication Date
Dec 01, 1999
Volume
53
Issue
6
Pages
253–257
Identifiers
PMID: 10631379
Source
Medline
License
Unknown

Abstract

To better understand the nature of the symptoms of depression in the early stages of Pick's disease, we performed a retrospective study of the medical records of eight patients who were originally treated for major depressive disorders before being clinically diagnosed with Pick's disease. Six of the eight manifested psychomotor retardation and social withdrawal, seven of the eight were agitated and five of the eight showed hyperbulia too. However, only two of the eight showed melancholia or physical symptoms such as insomnia or loss of appetite. All patients were treated with antidepressants but these were not effective in relieving the symptoms of depression. The data we gathered in this study will be useful in the future for distinguishing between Pick's disease-related depression (in the early stages of the disease) and major depression.

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