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Dendritic Cells Can Initiate Protective Immune Responses against Malaria

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Publisher
American Society for Microbiology
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PMC
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Abstract

An understanding of the antigen presentation mechanisms that mediate induction of protective immune responses against malaria is essential for the development of successful immunization approaches. Here we show that dendritic cells presenting Plasmodium yoelii sporozoite antigens are able to activate specific CD4+ and CD8+ T cells and initiate protective immune responses against malaria in mice.

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