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[Demonstration of an inoculum effect on the estimation of the minimal inhibitory concentration of LY 146032].

Authors
  • Flandrois, J P
  • Carret, G
  • Pichat, C
  • Peyret, M
Type
Published Article
Journal
Pathologie Biologie
Publisher
Elsevier
Publication Date
May 01, 1988
Volume
36
Issue
5
Pages
377–380
Identifiers
PMID: 2841637
Source
Medline
License
Unknown

Abstract

This work has been performed to study the inoculum effect on the in vitro activity of LY 146032, a new lipopeptide antibiotic. A statistical analysis (X2 and t test) of the data concerning the MIC of different bacterial groups has been carried out to appreciate the phenomenon. The activity of vancomycin has been compared. A major inoculum effect has been detected for LY 146032. It must be taken into account to evaluate the activity of this new antibiotic.

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