[Demonstration of an inoculum effect on the estimation of the minimal inhibitory concentration of LY 146032].
- Authors
- Type
- Published Article
- Journal
- Pathologie Biologie
- Publisher
- Elsevier
- Publication Date
- May 01, 1988
- Volume
- 36
- Issue
- 5
- Pages
- 377–380
- Identifiers
- PMID: 2841637
- Source
- Medline
- License
- Unknown
Abstract
This work has been performed to study the inoculum effect on the in vitro activity of LY 146032, a new lipopeptide antibiotic. A statistical analysis (X2 and t test) of the data concerning the MIC of different bacterial groups has been carried out to appreciate the phenomenon. The activity of vancomycin has been compared. A major inoculum effect has been detected for LY 146032. It must be taken into account to evaluate the activity of this new antibiotic.
