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Demonstration of blood pressure-independent noninfarct myocardial fibrosis in primary aldosteronism: a cardiac magnetic resonance imaging study.

Authors
Type
Published Article
Journal
Circulation. Cardiovascular imaging
Publication Date
Volume
5
Issue
6
Pages
740–747
Identifiers
DOI: 10.1161/CIRCIMAGING.112.974576
PMID: 23019275
Source
Medline
License
Unknown

Abstract

These data illustrate that patients with PA exhibit frequent myocardial fibrosis as demonstrated by late gadolinium enhancement using cardiac magnetic resonance imaging; this finding is independent of blood pressure. This may be mediated partly through inflammation and oxidative stress. This study highlights the importance of specific targeting of aldosterone excess as well as blood pressure reduction to minimize cardiac morbidity in PA.

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