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[Dementia and fracture].

Authors
  • Sato, Yoshihiro
Type
Published Article
Journal
Clinical calcium
Publication Date
Sep 01, 2010
Volume
20
Issue
9
Pages
1379–1384
Identifiers
DOI: CliCa100913791384
PMID: 20808046
Source
Medline
License
Unknown

Abstract

A high incidence of fractures, particularly of the hip, represents an important problem in patients with AD, who are prone to falls and may have osteoporosis. The odds ratio reported for fracture prevalence between elderly persons with and without AD is 6.9. We previously demonstrated that deficiency of 25-hydroxyvitamin D due to sunlight deprivation and vitamin K deficiency due to malnutrition contributed to reduced bone mineral density in patients with AD and were associated with a high risk of hip fracture. Treatment with menatetrenone, risedronate or regular sunlight exposure are safe and effective in increasing bone mass and reducing the risk of hip fracture in patients with AD.

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