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Demeclocycline in the prophylaxis of self-induced water intoxication.

Authors
  • Nixon, R A
  • Rothman, J S
  • Chin, W
Type
Published Article
Journal
The American journal of psychiatry
Publication Date
Jun 01, 1982
Volume
139
Issue
6
Pages
828–830
Identifiers
PMID: 6805340
Source
Medline
License
Unknown

Abstract

Demeclocycline, a competitive inhibitor of antidiuretic hormone at renal tubules, was studied in a patient with the syndrome of psychosis, psychogenic polydipsia, and episodic water intoxication. Under double-blind, placebo-controlled conditions, demeclocycline substantially reduced the severity and frequency of hyponatremic episodes.

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