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[Delayed hypersensitivity to evoked antigens: normal values in Chilean young adults].

Authors
Type
Published Article
Journal
Revista médica de Chile
0034-9887
Publisher
SciELO Comision Nacional de Investigacion Cientifica Y Tecnologica
Publication Date
Volume
124
Issue
1
Pages
61–69
Identifiers
PMID: 8762620
Source
Medline

Abstract

Delayed hypersensitivity skin test are widely accepted as in vivo measure of cellular immunity. Since genetic and environmental factors may affect these tests, each population must establish its own normal values. The aim of this work was to study delayed hypersensitivity in Chilean normal young adults. We studied the response to eight antigens using the Multitest CMI (Rhodia Merieux) in 50 students (22 females, 28 males), aged 18 to 25 years old. Skin tests were read at 24, 48 and 72 hours. At 48 Hours, 60% of women responded to 3 and 68% of men to 4 antigens. A mean response to 3.6 antigens was observed. Total score in men and women were 19.5 +/- 7.3 and 12.2 +/- 6.5 mm respectively (p < 0.05). These figures are different from those published abroad and confirm the need for national standards.

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