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Delayed effect of hypotensive drugs on blood pressure and structure of the myocardium in hypertensive ISIAH rats during chronic stress.

Authors
Type
Published Article
Journal
Bulletin of experimental biology and medicine
Publication Date
Volume
147
Issue
4
Pages
485–488
Identifiers
PMID: 19704955
Source
Medline
License
Unknown

Abstract

Administration of antihypertensive drugs alpha(1)-adrenoceptor antagonist and Ca(2+) channel blocker during early ontogeny had various delayed effects on blood pressure in ISIAH rats with inherited stress-induced arterial hypertension under resting conditions and chronic stress. The drugs did not prevent the development of myocardial hypertrophy. Chronic stress had little effect on myocardial structure in adult animals.

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