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Delayed convergence between brain network structure and function in rolandic epilepsy.

Authors
  • Besseling, René M H
  • Jansen, Jacobus F A
  • Overvliet, Geke M
  • van der Kruijs, Sylvie J M
  • Ebus, Saskia C M
  • de Louw, Anton J A
  • Hofman, Paul A M
  • Aldenkamp, Albert P
  • Backes, Walter H
Type
Published Article
Journal
Frontiers in Human Neuroscience
Publisher
Frontiers Media SA
Publication Date
Jan 01, 2014
Volume
8
Pages
704–704
Identifiers
DOI: 10.3389/fnhum.2014.00704
PMID: 25249968
Source
Medline
Keywords
License
Unknown

Abstract

Since SC and FC converge during normal maturation, our finding of reduced SC-FC correlation illustrates impaired synergy between brain structure and function. More specifically, since this effect was most pronounced in the youngest participants, RE may represent a developmental disorder of delayed brain network maturation. The observed effects seem especially attributable to medial parietal connections, which forms an intermediate between bilateral centro-temporal modules of epileptiform activity, and bear relevance for language function.

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