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Quantitative determination of angiotensin II binding sites in rat brain and pituitary gland by autoradiography

Authors
Journal
Brain Research
0006-8993
Publisher
Elsevier
Publication Date
Volume
322
Issue
2
Identifiers
DOI: 10.1016/0006-8993(84)90130-6
Keywords
  • Angiotensin Ii Binding Sites
  • Radioautography
  • Quantitation Of Binding Sites
  • Brain
  • Pituitary Gland
  • Organon Subfornicalis

Abstract

Abstract Rat brain and pituitary angiotensin II (AII) binding sites were quantitated by incubation of tissue sections with 125I-[Sar 1] AII, Ultrofilm radioautography, computerized densitometry, and comparison with 125I-standards at appropriate film exposure times. The highest number of AII binding sites was found in anterior pituitary and the circumventricular organs, organon subfornicalis and organon vasculosum laminae terminalis.

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