Affordable Access

deepdyve-link
Publisher Website

A decrease of the butyrate-producing species Roseburia hominis and Faecalibacterium prausnitzii defines dysbiosis in patients with ulcerative colitis.

Authors
  • Machiels, Kathleen
  • Joossens, Marie
  • Sabino, João
  • De Preter, Vicky
  • Arijs, Ingrid
  • Eeckhaut, Venessa
  • Ballet, Vera
  • Claes, Karolien
  • Van Immerseel, Filip
  • Verbeke, Kristin
  • Ferrante, Marc
  • Verhaegen, Jan
  • Rutgeerts, Paul
  • Vermeire, Séverine
Type
Published Article
Journal
Gut
Publisher
BMJ
Publication Date
Aug 01, 2014
Volume
63
Issue
8
Pages
1275–1283
Identifiers
DOI: 10.1136/gutjnl-2013-304833
PMID: 24021287
Source
Medline
Keywords
License
Unknown

Abstract

The composition of the fecal microbiota of UC patients differs from that of healthy individuals: we found a reduction in R hominis and F prausnitzii, both well-known butyrate-producing bacteria of the Firmicutes phylum. These results underscore the importance of dysbiosis in IBD but suggest that different bacterial species contribute to the pathogenesis of UC and CD.

Report this publication

Statistics

Seen <100 times