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A Deceptive Spread: Myoinvasion of Endometrial Carcinoma Imitating Adenoma Malignum.

Authors
  • Deb, Pratik Q1
  • Marcus, Jenna Z1
  • Abedin, Yasmin1
  • Heller, Debra S1
  • 1 Rutgers-New Jersey Medical School, Newark, NJ, USA. , (Jersey)
Type
Published Article
Journal
International journal of surgical pathology
Publication Date
Nov 05, 2019
Identifiers
DOI: 10.1177/1066896919886113
PMID: 31690149
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Endometrioid type of endometrial carcinoma is the most common form of uterine malignancy. The majority of patients in the developed world present with the low-grade, low-stage type of this malignancy. The current treatment of early-stage endometrioid carcinoma provides most patients with a favorable outcome. One of the important factors that determine the outcome of early-stage endometrial carcinoma is the involvement of cervical stroma. One of the very rare forms of cervical stromal involvement by endometrioid carcinoma is termed "adenoma malignum type" invasion due to its similarity to the infamously deceptive type of cervical adenocarcinoma called adenoma malignum. Since adenoma malignum is often discovered incidentally, finding adenoma malignum type of myoinvasion may deceive a pathologist to diagnose the simultaneous presence of endometrial carcinoma and adenoma malignum in the same patient as 2 separate entities. Also, this type of myoinvasion may be missed altogether for its subtle nature. In this article, we report a case of low-grade, low-stage endometrioid carcinoma with adenoma malignum type of myoinvasion. We have pointed out the subtle nature of this lesion and the important features to remember to successfully identify it.

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