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Dead space ventilation parallels changes in scintigraphic vascular obstruction at recurrence of pulmonary embolism and after thrombolytic therapy: a case report.

Authors
  • Rodger, M A1
  • Jones, G
  • Raymond, F
  • Lalonde, D
  • Proulx, M
  • Huebsch, L
  • Bredeson, C
  • 1 Ottawa General Hospital, University of Ottawa, Ottawa, Canada. , (Canada)
Type
Published Article
Journal
Canadian respiratory journal
Publication Date
Jan 01, 1998
Volume
5
Issue
3
Pages
215–218
Identifiers
PMID: 9707468
Source
Medline
License
Unknown

Abstract

Physiological and alveolar dead space ventilation both increase in pulmonary embolism (PE) in proportion to the severity of vascular obstruction. The case of a patient with recurrent PE while on heparin therapy is presented. The recurrence was characterized clinically by severe pulmonary vascular obstruction and right heart dysfunction. The patient was treated with thrombolytic therapy, with excellent clinical and scintigraphic resolution. Dead space ventilation measurements at baseline, at the time of recurrence and after thrombolytic therapy are presented. The potential utility of dead space ventilation measurements for PE diagnosis and management are discussed.

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