Affordable Access

What makes silica toxic?

Authors
Publication Date
Keywords
  • Research Article
Disciplines
  • Medicine

Abstract

Published data suggest that particle charge could be related to its toxicity. Respirable particles containing silica were therefore collected in foundries and their charge measured. These particles carried high levels of positive charge that were related to low humidity. Incubating these particles with pulmonary macrophages from mice produced detectable activities of collagenase, a precursor of silicosis. These experiments confirm that the toxicity of silica particles is likely to be because of the positive charge they carry.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments

More articles like this

What makes silica toxic?

on British journal of industrial... March 1992

What makes a toxicologist?

on Regulatory toxicology and phar... December 1996

What makes a human?

on The New Scientist Jun 26, 1999
More articles like this..