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Two lignans, one alkaloid, and flavanone from the twigs ofFeroniella lucida

Authors
Journal
Tetrahedron
0040-4020
Publisher
Elsevier
Publication Date
Volume
70
Issue
9
Identifiers
DOI: 10.1016/j.tet.2014.01.023
Keywords
  • Feroniella Lucida
  • Lignans
  • Alkaloids
  • Flavanone
  • Biosynthetic

Abstract

Abstract Four new compounds, two lignans; lucidenal and lucidanin (1 and 2), one alkaloid (3), and one flavanone (4) together with 26 known compounds (5–30), were isolated from the twigs of Feroniella lucida. The structures of the new compounds were determined on the basis of spectroscopic analyses. Lucidenal 1 showed cytotoxicity against HuCCA-1, A549, MOLT-3 and HepG2 cancer cell lines with IC50 values of 4.27, 9.59, 2.31, and 6.50 μg/mL, respectively. A plausible biosynthetic pathway of 1 was proposed.

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