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Determination of pulsatile flow rates by indicator-dilution methods

Authors
Journal
Journal of Theoretical Biology
0022-5193
Publisher
Elsevier
Publication Date
Volume
50
Issue
2
Identifiers
DOI: 10.1016/0022-5193(75)90086-7
Disciplines
  • Mathematics

Abstract

Abstract A new method is proposed for measuring nonsteady flow rates when this flow is pulsatile in nature. This method involves the use of indicators and does not require direct access to the vessel carrying the fluid. No knowledge of the associated mathematics is required for its application. The investigator infuses indator into the vessel leading into a capillary or similar labyrinth at a time-varying rate such that the indicator concentration at the outflow from the labyrinth remains constant in time. When this condition at the outflow has been achieved, the pulsatile flow rate at the inflow is given simply as the ratio of the varying infusion rate to the constant outflow indicator concentration.

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