Affordable Access

Effectiveness of sertraline in treatment of depression in a consecutive sample of patients with acute myocardial infarction: six month prospective study on outcome

Authors
Publisher
BioMed Central
Publication Date
Source
PMC
Keywords
  • Research
Disciplines
  • Medicine

Abstract

1745-0179-1-26.fm ral Clinical Practice and Epidemiology ss BioMed Centin Mental Health Open AcceResearch Effectiveness of sertraline in treatment of depression in a consecutive sample of patients with acute myocardial infarction: six month prospective study on outcome Prasanta Kumar Mohapatra1, Nilamadhab Kar*2, Gopal Chandra Kar3 and Mrutyunjaya Behera4 Address: 1Consultant Psychiatrist, Mental Health Institute, SCB Medical College, Cuttack, India, 2Consultant psychiatrist, Corner House Resource Centre, 300, Dunstall Road, Wolverhampton, WV6 0NZ, UK, 3Professor and Head of Department of Psychiatry, Mental Health Institute, SCB Medical College, Cuttack, India and 4Professor and Head of Cardiology, SCB Medical College, Cuttack, India Email: Prasanta Kumar Mohapatra - [email protected]; Nilamadhab Kar* - [email protected]; Gopal Chandra Kar - [email protected]; Mrutyunjaya Behera - [email protected] * Corresponding author Abstract Background: A considerable proportion of patients suffer from depression following acute myocardial infarction. Information regarding this prevalence in Indian patients and response to treatment is lacking. Method: Prevalence of major depression was studied in 50 consecutive in-patients with acute myocardial infarction following DSM-IV criteria. In a comparative study outcome of treatment with sertraline in terms of recovery from depression, change in Hamilton Depression Rating scale score and occurrence of cardiac events were ascertained for a 6-month period, which were compared with a group of patients who did not receive sertraline. Results: Major depression was diagnosed in 34% of patients. Female patients were more affected than the males. Hamilton Depression Rating scale scores gradually decreased in both the groups over the study period; however it became significantly less for patients treated with sertraline. Significantly more number of patients who received sertraline recovered from depression. There were no dropout

There are no comments yet on this publication. Be the first to share your thoughts.