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Clinical laboratory studies on a new topical corticosteroid—Triamcinolone acetonide

Authors
Journal
Oral Surgery Oral Medicine Oral Pathology
0030-4220
Publisher
Elsevier
Publication Date
Volume
14
Issue
8
Identifiers
DOI: 10.1016/0030-4220(61)90007-x
Keywords
  • Oral Medicine
Disciplines
  • Chemistry
  • Medicine

Abstract

Abstract Triamcinolone acetonide, a new corticosteroid which has been suggested as a highly active topical agent in the treatment of certain acute and chronic lesions of the oral mucous membranes, was studied with respect to its possible systemic actions. In order to determine any undesirable effects incident to topical therapy, we undertook detailed blood chemistry, hematologic, and urine studies in eleven patients treated with this corticosteroid. A comparative study of the before- and after-treatment blood and urine test values following the five-day period of drug therapy (including 1 mg. per day of the active agent, triamcinolone acetonide) did not reveal any discernible or noteworthy deviations. All test findings remained within the accepted normal range. Where posttherapy deviations within the normal range were found, no consistent pattern was evident.

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