Affordable Access

Publisher Website

Mannheimia haemolyticaserotype 1 andPasteurella trehalosiserotype 10 culture supernatants contain fibrinogen-binding proteins

Authors
Journal
Veterinary Immunology and Immunopathology
0165-2427
Publisher
Elsevier
Publication Date
Volume
90
Identifiers
DOI: 10.1016/s0165-2427(02)00222-2
Keywords
  • Fibrinogen-Binding Protein
  • Pasteurellosis
  • Mannheimia Haemolytica
  • Pasteurella Trehalosi
  • Virulence Factor
Disciplines
  • Biology

Abstract

Abstract Fibrinogen-binding proteins were found in the culture supernatants of Mannheimia haemolytica serotype 1 (ATCC 43270) and Pasteurella trehalosi serotype 10 (ECO-100). Sheep fibrinogen was biotinylated and shown to bind to proteins in the culture supernatants by modified western blot. Fibrinogen-binding proteins in the culture supernatant may be important virulence factors leading to the characteristic fibrinous pneumonia caused by these organisms and may be critical antigenic targets for immune prophylaxis.

There are no comments yet on this publication. Be the first to share your thoughts.