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Palladium-catalyzed amination of 3-bromo-4-fluoro-acetophenone

Authors
Journal
Tetrahedron Letters
0040-4039
Publisher
Elsevier
Publication Date
Volume
43
Issue
51
Identifiers
DOI: 10.1016/s0040-4039(02)02384-5

Abstract

Abstract The palladium-catalyzed amination of 3-bromo-4-fluoro-acetophenone was found to predominate over both the 4-fluoro nucleophilic substitution with amines and the palladium-catalyzed α-arylation of the acetyl group.

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