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Y-SNP-genotyping – a new approach in forensic analysis

Authors
Journal
Forensic Science International
0379-0738
Publisher
Elsevier
Publication Date
Volume
154
Identifiers
DOI: 10.1016/j.forsciint.2004.09.129
Keywords
  • Y-Chromosomal Snp
  • Minisequencing
  • Snapshot
  • Maldi-Tof Ms
  • Stain Analysis
Disciplines
  • Anthropology
  • Criminology

Abstract

Abstract Y-chromosomal DNA polymorphisms, especially Y-STRs are well established in forensic routine case work. The STRs are used for identification in paternity deficiency cases and stain analysis with complicate mixtures of male and female DNA. In contrast, Y-chromosomal SNPs are a new tool in forensic investigations. At present, Y-SNPs are mainly used in molecular anthropology for evolutionary studies. Nevertheless, these markers could also provide very useful information for the analysis of forensic cases. The aim of the presented study was to test Y-SNP-typing for stain analyses using different methods—SNaPshot and MALDI-TOF MS. Both methods are based on the principle of minisequencing. The selected Y-SNP markers are suited to define the most important European haplogroups.

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