Affordable Access

Intravenous prednisolone in chronic bronchial asthma.

Authors
Journal
Thorax
0040-6376
Publisher
BMJ
Publication Date
Keywords
  • Research Article
Disciplines
  • Medicine

Abstract

A single injection of 40 mg prednisolone phosphate was given to 10 patients with chronic bronchial asthma. Changes in pulmonary function were followed over a 30-hour period. Statistically significant changes occurred in the tests employed one hour after the injection of prednisolone. The maximum change for the group as a whole was seen to occur after eight hours. This time course of response is very similar to that obtained in previous studies on similar groups of patients with oral prednisolone where the peak effect occurred nine hours after the drug had been given. Intravenous hydrocortisone produces a much earlier peak effect, at five hours, when it is administered to chronic asthmatic patients.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments

More articles like this

TREATMENT OF SEVERE BRONCHIAL ASTHMA AND STATUS AS...

on Therapia Hungarica (English ed... 1965

The effect of oral prednisolone on gas exchange in...

on British journal of clinical ph... May 1980

The time-course of response to prednisolone in chr...

on Clinical science and molecular... August 1974
More articles like this..