Affordable Access

Publisher Website

Prolonged apnea during electroconvulsive therapy in monozygotic twins: case reports

Authors
Journal
Annals of General Psychiatry
1744-859X
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Volume
10
Issue
1
Identifiers
DOI: 10.1186/1744-859x-10-30
Source
Legacy
Keywords
  • Case Report
Disciplines
  • Medicine

Abstract

In the present work, we report two cases of monozygotic twins who developed prolonged apnea during electroconvulsive therapy (ECT) as a complication of anesthesia. In both cases, prolonged action of succinylcholine caused by a butyrylcholinesterase (BCHE) deficiency was confirmed by means of the dibucaine number test. In both cases, genetic analysis using the polymerase chain reaction revealed haplotype combined A and K variant mutations of the BCHE gene, both in the heterozygous form. These data show the potential risk of BCHE deficiency as a complication of anesthesia during ECT, and in particular underline the possible genetic contribution within a complex pathogenetic model.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments