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The synthesis of some N-phosphoryldipeptide aldehydes

Authors
Journal
Biochemical and Biophysical Research Communications
0006-291X
Publisher
Elsevier
Publication Date
Volume
96
Issue
1
Identifiers
DOI: 10.1016/0006-291x(80)91195-x
Disciplines
  • Biology

Abstract

Abstract Four N-phosphoryldipeptide aldehydes have been synthesized and tested in vitro against thermolysin and trypsin. Their structures exemplify a combination of leupeptin and phosphoramidan structures into one molecule which then shows enzyme inhibition.

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