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A possible mechanism of RNA replication in Rous sarcoma virus

Authors
Publisher
Okayama University Medical School
Publication Date
Disciplines
  • Biology

Abstract

Partially separated double-stranded RNA from purified Rous sarcoma virus, Schmidt.Ruppin strain, was observed by electron microscopy utilizing 8.M urea and protein monolayer technique. Furthermore, viruses in pair were frequently and viruses with two nuc1eoids were occasionally observed in ultrathin. sectioned specimens of chick cells transformed by RSV. From these results taking other reports in consideration, a possible mechanism of RNA replication in Rous sarcoma virus is proposed.

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