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Complementing Thymidylate Synthase

Authors
Journal
Structure
0969-2126
Publisher
Elsevier
Publication Date
Volume
11
Issue
6
Identifiers
DOI: 10.1016/s0969-2126(03)00101-1
Disciplines
  • Biology
  • Design
  • Medicine

Abstract

Abstract The structure of thymidylate synthase complementing protein with substrates dUMP and FAD, presented in this issue of Structure, sheds light on a fascinating new catalytic mechanism, suggests a strategy for the design of new antimicrobial compounds, and highlights the promise of proteomics in medicine.

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