Long Non-Coding RNA in Cancer

Affordable Access

Long Non-Coding RNA in Cancer

Multidisciplinary Digital Publishing Institute
  • Cancer
  • Long Non-Coding Rna
  • Oncogenic Lncrna
  • Tumor Suppressor Lncrna


Long non-coding RNAs (lncRNAs) are pervasively transcribed in the genome and are emerging as new players in tumorigenesis due to their various functions in transcriptional, posttranscriptional and epigenetic mechanisms of gene regulation. LncRNAs are deregulated in a number of cancers, demonstrating both oncogenic and tumor suppressive roles, thus suggesting their aberrant expression may be a substantial contributor in cancer development. In this review, we will summarize their emerging role in human cancer and discuss their perspectives in diagnostics as potential biomarkers.

There are no comments yet on this publication. Be the first to share your thoughts.


Seen <100 times

More articles like this

Long non-coding RNA in cancer.

on International Journal of Molec... 2013

Long non-coding RNAs era in liver cancer.

on World journal of hepatology Aug 08, 2015

Long non-coding RNAs in cancer.

on Science China. Life sciences December 2012
More articles like this..