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One-pot synthesis of aryl glycines and other unnatural amino acids from serine derivatives

Authors
Journal
Tetrahedron Letters
0040-4039
Publisher
Elsevier
Publication Date
Volume
43
Issue
46
Identifiers
DOI: 10.1016/s0040-4039(02)02023-3
Keywords
  • Aryl Glycines
  • Unnatural Amino Acids
  • Alkoxyl Radicals
  • Fragmentation
  • Nucleophilic Addition
  • N-Acyliminium Ions

Abstract

Abstract A mild and highly efficient one-pot synthesis of aryl glycines from easily available serine derivatives is described. This methodology is also applied to the synthesis of other uncommon amino acids.

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