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The role of acetone in the conversion of fat to carbohydrate

Authors
Journal
Trends in Biochemical Sciences
0968-0004
Publisher
Elsevier
Publication Date
Volume
12
Identifiers
DOI: 10.1016/0968-0004(87)90051-x

Abstract

Abstract Argilés recently reviewed 1 some of the evidence supporting the concept that acetone is an intermediate in the conversion of fat to carbohydrate. He dealt with the conversion of acetone to glucose via lactate and its metabolic equivalent, pyruvate. He did not discuss the large body of evidence showing that the carbons from acetone are also incorporated into glucose via acetate. This is important in interpreting studies of the role of acetone in glucose formation, and is the subject of this review.

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