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EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF); Scientific Opinion on Flavouring Group Evaluation 08, Revision 4 (FGE.08Rev4): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30

Authors
Publisher
European Food Safety Authority
Publication Date
Keywords
  • The Panel On Food Contact Materials
  • Enzymes
  • Flavourings And Processing Aids Of The European Food Safety Authority Was Requested To Evaluate 80 F
  • Revision 4
  • Using The Procedure In Commission Regulation (Ec) No 1565/2000
  • Since The Publication Of The Last Revision Of This Fge
  • The Efsa Has Been Requested To Evaluate 10 Additional Substances
  • Which Have Been Included In The Present Revision Of Fge
  • 08
  • For The Substances Methyl Methanethiosulphonate [Fl-No: 12
  • 159]
  • 2-Methylbutane-2-Thiol [Fl-No: 12
  • 172]
  • 2-Methylpropane-2- Thiol [Fl-No: 12
  • 174]
  • Ethyl 2-Mercapto-2-Methyl Propanoate [Fl-No: 12
  • 304] And 2
  • 4
  • 4-Trimethyl-1
  • 3- Oxathiane [Fl-No: 16
  • 057] There Is An Indication Of A Genotoxic Potential In Vitro
  • Therefore
  • In The Absence Of Further Genotoxicity Data
  • The Panel Concluded That The Procedure Could Not Be Applied To These Five Substances
  • For Four Substances
  • 3-Mercaptooctanal [Fl-No: 12
  • 268]
  • 3-Mercaptodecanal [Fl-No: 12
  • 269]
  • Methanedithiol Diacetate [Fl-No: 12
  • 271] And 3
  • 5-Dimethyl-1
  • 2-Dithiolane-4-One [Flno: 12
  • 295] No Data On Use As Flavouring Substances In Europe Are Available
  • Therefore
  • No Intakes In Europe Can Be Estimated And Accordingly The Panel Concluded That The Procedure Could N
  • The Remaining 71 Substances Were Evaluated Through A Stepwise Approach That Integrates Information O
  • Intake From Current Uses
  • Toxicological Threshold Of Concern
  • And Available Data On Metabolism And Toxicity
  • The Panel Concluded That 57 Substances Do Not Give Rise To Safety Concerns At Their Levels Of Dietar
  • <Br/>Estimated On The Basis Of The Msdi Approach
  • For The Remaining Fourteen Substances [Fl-No: 12
  • 093
  • 12
  • 094
  • 12
  • 097
  • 12
  • 100
  • 12
  • 112
  • 12
  • 116
  • 12
  • 120
  • 12
  • 164
  • 12
  • 167
  • 12
  • 199
  • 15
  • 007
  • 15
  • 102 And 15
  • 125 And 15
  • 134]
  • Evaluated Through The Procedure
  • No Appropriate Noael Was Available And Additional<Br/>Data Are Required
  • Besides The Safety Assessment Of The Flavouring Substances
  • The Specifications For The Materials Of Commerce Have Also Been Considered And For 21 Substances
  • Evaluated Through The Procedure
  • Information On The Stereoisomeric/Positional Composition And/Or The Specifications Is Lacking
Disciplines
  • Chemistry

Abstract

EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF); Scientific Opinion on Flavouring Group Evaluation 08, Revision 4 (FGE.08Rev4): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 - DTU Orbit (26/04/14) EFSA publication (2012). EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF); Scientific Opinion on Flavouring Group Evaluation 08, Revision 4 (FGE.08Rev4): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30. Parma, Italy: European Food Safety Authority. (The EFSA Journal; No. 2455, Vol. 10(2)). 10.2903/j.efsa.2012.2455

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