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Effect ofEnalaprilon Left Ventricular Diameters and Exercise Capacity in Asymptomatic or Mildly Symptomatic Patients With Regurgitation Secondary to Mitral Valve Prolapse or Rheumatic Heart Disease

Authors
Journal
The American Journal of Cardiology
0002-9149
Publisher
Elsevier
Publication Date
Volume
96
Issue
1
Identifiers
DOI: 10.1016/j.amjcard.2005.02.056
Disciplines
  • Medicine

Abstract

The effects of 12 months of therapy were evaluated in 47 mildly symptomatic patients with moderate to severe mitral valve regurgitation; 26 patients received enalapril and 21 received a placebo. Enalapril was associated with a significant reduction in left ventricular diameter and mitral regurgitation volume, with no evidence of change in systolic function indexes. However, enalapril did not hinder progressive aerobic impairment to effort.

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