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Recessive-lethal nonsense suppressors inSalmonella typhimurium

Authors
Journal
Journal of Molecular Biology
0022-2836
Publisher
Elsevier
Publication Date
Volume
59
Issue
1
Identifiers
DOI: 10.1016/0022-2836(71)90413-x

Abstract

Abstract A recessive-lethal UGA suppressor and a recessive-lethal amber suppressor have been characterized in strains of Salmonella typhimurium merodiploid for the ilvmetE region of the chromosome. Both suppressors are greater than 50% efficient and both are co-transducible with ilvE. The suppressors can be transduced into haploid strains but the transductants are unstable and appear to contain duplications of the sup locus. The amber suppressor and the UGA suppressor appear to arise from a common gene.

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