Abstract The article describes the features of biogerontology research in Spain and outlines the research in the biology of ageing, covering a wide spectrum of areas and topics. Research in biogerontology has expanded notably in quality and quantity in the last decades with the development of internationally recognized research groups actively working in the analysis of the complex process of ageing. In the last few years research in ageing has become a priority area in the National Program of Research which has substantially increased funds specifically allocated to biogerontology and biological research on senescence. Despite these improvements, special efforts have to be made not only to consolidate the existing groups but also to facilitate the initiation and development of new research groups in Universities, Hospitals and research institutions with capacity to incorporate trained researchers in this area. It would promote the continuous incorporation of technical and scientific advances in other disciplines to the understanding the biology of ageing and the molecular basis of cellular senescence, that will benefit actual and future ageing population.