Affordable Access

Publisher Website

Tissue-type plasminogen activator and Type-1 plasminogen activator inhibitor in patients with coronary artery disease — Relations to clinical variables and cardiovascular risk factors

Authors
Journal
Fibrinolysis and Proteolysis
0268-9499
Publisher
Elsevier
Publication Date
Volume
9
Identifiers
DOI: 10.1016/s0268-9499(08)80100-2
Disciplines
  • Medicine

Abstract

Summary In this study we investigated associations of the fibrinolytic parameters t-PA antigen and PAI-1 activity in 317 patients with angiographically proven coronary artery disease with gender, age classes, angiographic extent of disease, symptom class and history of myocardial infarction as clinical parameters, as well as with the established cardiovascular risk factors: smoking, arterial hypertension, cholesterol levels, triglyceride levels, obesity and diabetes mellitus, by use of univariate and multifactorial analysis, respectively. While PAI-1 activity was only associated with unstable angina, t-PA antigen was significantly associated with hypertriglyceridemia, unstable angina, and angiographic extent of disease.

There are no comments yet on this publication. Be the first to share your thoughts.