Abstract We report the results of a search for pair production of scalar bottom quarks (b˜1) and scalar third-generation leptoquarks (LQ3) in 5.2 fb−1 of pp¯ collisions at the D0 experiment of the Fermilab Tevatron Collider. Scalar bottom quarks are assumed to decay to a neutralino (χ˜10) and a b quark, and we set 95% C.L. lower limits on their production in the (mb˜1, mχ˜10) mass plane such as mb˜1>247 GeV for mχ˜10=0 and mχ˜10>110 GeV for 160<mb˜1<200 GeV. The leptoquarks are assumed to decay to a tau neutrino and a b quark, and we set a 95% C.L. lower limit of 247 GeV on the mass of a charge-1/3 third-generation scalar leptoquark.