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Allopurinol in the treatment of acquired reactive perforating collagenosis*

Authors
Publisher
Sociedade Brasileira de Dermatologia
Publication Date
Volume
88
Issue
1
Identifiers
DOI: 10.1590/s0365-05962013000100012
Source
Legacy
Keywords
  • Case Report
Disciplines
  • Medicine

Abstract

Acquired reactive perforating collagenosis is a perforating dermatosis usually associated with different systemic diseases, mainly diabetes mellitus and/or chronic renal insufficiency. Different therapies have been tried but treatment is not standardized yet and remains a challenge. In the last few years, allopurinol has been reported as a good therapeutic option for acquired reactive perforating collagenosis. We describe the case of a 73-year-old man affected by acquired reactive perforating collagenosis associated with diabetes type 1 and chronic renal failure with secondary hyperparathyroidism. The patient was successfully treated with allopurinol 100mg once/day p.o..

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