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Stereoselective synthesis of (−)-cytoxazone

Authors
Publisher
Elsevier Ltd
Publication Date
Volume
12
Issue
14
Identifiers
DOI: 10.1016/s0957-4166(01)00340-8

Abstract

Abstract A novel stereoselective synthesis of (−)-cytoxazone 1 was achieved via addition of p-methoxyphenylmagnesium bromide to the benzylimine derived from ( S)-2,3- O-isopropylidene glyceraldehyde followed by one-step regioselective cyclization of N-Boc amino diol 7.

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