Affordable Access

Evidence from Insect Fibrillar Muscle about the Elementary Contractile Process

Authors
Journal
The Journal of General Physiology
0022-1295
Publisher
The Rockefeller University Press
Publication Date
Keywords
  • Comparative Aspects Of Muscular Contraction
  • Article
Disciplines
  • Chemistry

Abstract

Bundles of myofibrils prepared from the dorsal longitudinal flight muscles of giant water bugs show oscillatory contractile activity in solutions of low ionic strength containing ATP and 10-8-10-7 M Ca2+. This is due to delay between changes of length and changes of tension under activating conditions. The peculiarities of insect fibrillar muscle which give rise to this behavior are (1) the high elasticity of relaxed myofibrils, (2) a smaller degree of Ca2+ activation of ATPase activity in unstretched myofibrils and extracted actomyosin, and (3) a direct effect of stretch on ATPase activity. It is shown that the cross-bridges of striated muscle are probably formed from the heads of three myosin molecules and that in insect fibrillar muscle the cycles of mechanochemical energy conversion in the cross-bridges can be synchronized by imposed changes of length. This material is more suitable than vertebrate striated muscle for a study of the nature of the elementary contractile process.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments

More articles like this

Evidence from insect fibrillar muscle about the el...

on The Journal of General Physiol... July 1967

The contractile mechanism of insect fibrillar musc...

on Progress in biophysics and mol... 1967

The activating effects of calcium ions on the cont...

on Pflügers Archiv für die gesa... 1966

Preparation and properties of the contractile elem...

on Journal of Cell Science September 1966
More articles like this..