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Synthesis of deuterium labeled polyunsaturated fatty acids

Authors
Journal
Tetrahedron Letters
0040-4039
Publisher
Elsevier
Publication Date
Volume
35
Issue
51
Identifiers
DOI: 10.1016/0040-4039(94)88495-1

Abstract

Abstract Compounds containing carbon-carbon double bonds bearing cis deuterium atoms can be prepared conveniently by treating disubstituted acetylenes with bis(2-deuteriocyclohexyl)borane-B-D 1 [DB(Cy) 2] followed by reaction with CH 3CO 2D. As an example, the preparation of labeled linolenic acid is reported.

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