Cytotoxic triterpenes from Ligulariopsis shichuana.
- Published Article
- Publication Date
Feb 01, 2003
Five olean-12-ene triterpenes (1-5) were isolated from the whole plant of Ligulariopsis shichuana. Their structures were elucidated by spectroscopic methods, including IR, EIMS positive HRSIMS, 1DNMR, and 2DNMR. Among them, 16beta,28-dihydroxyolean-12-en-3-one (3), olean-12-en-3beta,6beta,16beta,28-tetraol (4), 6beta,16beta-dihydroxyolean-12-en-3-one (5) are new compounds. In addition, compounds 4 and 5 showed cytotoxic activities on human hepatomacells (SMMC-7721), human ovarian neoplasm cells (HO-8910) and human hepatocytes cells (LO2).
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/12641335