Affordable Access

Cytotoxic triterpenes from Ligulariopsis shichuana.

Authors
Type
Published Article
Journal
Die Pharmazie
Publication Date
Volume
58
Issue
2
Pages
148–150
Identifiers
PMID: 12641335
Source
Medline

Abstract

Five olean-12-ene triterpenes (1-5) were isolated from the whole plant of Ligulariopsis shichuana. Their structures were elucidated by spectroscopic methods, including IR, EIMS positive HRSIMS, 1DNMR, and 2DNMR. Among them, 16beta,28-dihydroxyolean-12-en-3-one (3), olean-12-en-3beta,6beta,16beta,28-tetraol (4), 6beta,16beta-dihydroxyolean-12-en-3-one (5) are new compounds. In addition, compounds 4 and 5 showed cytotoxic activities on human hepatomacells (SMMC-7721), human ovarian neoplasm cells (HO-8910) and human hepatocytes cells (LO2).

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments