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[Cytotoxic cytokines in multiple sclerosis].

Authors
  • Głabiński, A
Type
Published Article
Journal
Neurologia i neurochirurgia polska
Publication Date
Jan 01, 1993
Volume
27
Issue
6
Pages
869–875
Identifiers
PMID: 8164782
Source
Medline
License
Unknown

Abstract

Cytokines are essential mediators of cell-to-cell communication in many physiological and pathophysiological processes. During the last few years a lot of data has accumulated suggesting that some of them may be involved in the pathomechanism of multiple sclerosis (MS). One of the most extensively studied is a cytotoxic cytokine--tumour necrosis factor (THF) which has demyelinating activity in vitro and in vivo. Similar in structure and functions is another cytotoxic cytokine-lymphotoxin (LT). In the article recent information about studies of TNF and LT in MS were reviewed.

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