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Cytonemes in development

Authors
  • Zhang, Chengting
  • Scholpp, Steffen
Type
Published Article
Journal
Current Opinion in Genetics & Development
Publisher
Elsevier
Publication Date
Aug 01, 2019
Volume
57
Pages
25–30
Identifiers
DOI: 10.1016/j.gde.2019.06.005
PMID: 31404787
PMCID: PMC6838781
Source
PubMed Central
License
Unknown

Abstract

Cell–cell communication is essential during the development of multicellular organisms. Specialized cell protrusions called cytonemes have been identified to exchange signals between cells that are vital for tissue development. Cytonemes can carry signalling components between distant cells and thus regulate the activity levels of the corresponding signalling pathways across entire tissues. This review summarizes the key findings on the formation and function of cytonemes in tissue development.

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