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Cytolytic degeneration of keratinocytes adjacent to Langerhans cells in pityriasis rosea (Gibert).

Authors
Type
Published Article
Journal
Acta Dermato Venereologica
0001-5555
Publisher
Acta Dermato-Venereologica
Publication Date
Volume
56
Issue
2
Pages
99–103
Identifiers
PMID: 58531
Source
Medline
License
Unknown

Abstract

Unique cytolytic degeneration of keratinocytes adjacent to Langerhans cells was observed in five cases of pityriasis rosea (Gilbert). In the cytolytic area, the normal keratinocyte structures were absent except for free ribosomes. In addition, a similar cytolytic part of a keratinocyte was enveloped by the elongated dendrites of the Langerhans cell and was detected within its cytoplasm. The significance of these findings is discussed with respect to anticytoplasmic antibodies in the sera of patients with pityriasis rosea.

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