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Cytologic distinction of goiterous nodules from morphologically normal thyroid: analyses of cytomorphologic features.

Authors
  • Layfield, Lester J
  • Wax, Tim
  • Jones, Claudia
Type
Published Article
Journal
Cancer
Publication Date
Aug 25, 2003
Volume
99
Issue
4
Pages
217–222
Identifiers
PMID: 12925983
Source
Medline
License
Unknown

Abstract

The results of the current study indicate that there are cytologic differences between FNA specimens from normal thyroid and from goiterous nodules. The presence of Hürthle cells, prominent nucleoli, and cells with abundant cytoplasm favored the diagnosis of nodular goiter, whereas large numbers of cells with paravacuolar granules favored a determination of histologically normal thyroid. These differences may aid in the distinction of normal thyroid tissue from hyperplastic goiters in cytologic specimens obtained by FNA.

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